The importance of Pharmad Clinical Information Processing in evaluating product performance

The performance of a product is often determined under the most ideal conditions in a randomized controlled trial. The performance observed in such tests can be considered as the highest performance for the product under consideration. However, under farm conditions, many uncontrollable influencing factors can interact with that outcome.

Therefore, the results in realistic field conditions, known as crop performance, can deviate greatly from those observed in controlled experiments.

To be able to evaluate this performance, monitoring farm conditions in sufficient detail is critical.

In this regard, Aviapp, Huvepharma Health Platform, can be a useful tool to answer such questions.

In this paper, the data collected by Aviapp have been used to evaluate the efficacy of reducing the level of coccidiosis damage in treatment with amprelium and reducing dysbacteriosis with various antimicrobial therapies.

The data used for the analysis were obtained from commercial meat farms in Belgium, which were studied between January 2019 and February 2020.

Available information includes coccidiosis damage grading according to the Johnson & Reed system in 1970. Dysbacteriosis levels collected by Aviapp are as good as information on drug use and its symptoms.

Finally, 1103 herd data were available. This set of information was used as a starting point to answer related questions.

Reducing the level of coccidiosis using amprelium

Out of 1103 herds, 83 herds were re-selected for grading. There was a great feature for the treatment group (53 herds) and that was that the first grading was done on the first day of the experiment. The average total damage (TMLS) classification in treated herds (53) was compared with untreated herds (30).

Most herds treated with amprolium showed a decrease in TMLS. In contrast, herds that were not treated with any combination showed an increase in the same age range. Untreated is shown in Figure 1.

Each herd is represented by a black line that connects to the study points. Purple lines indicate a moderate tendency in TMLS evaluation.

TMLS level assessment between the first and last point showed a 65% decrease in the treated groups while a 38% increase in the untreated groups.

This information confirms the efficacy of Pharma Amprolium as a treatment for coccidiosis.

Evaluation of dysbacteriosis in herds receiving different antibiotics

Of the 381 herds surveyed, 190 received treatment for enteritis / dysbacteriosis. For each of these herds, a grading report with a level of dysbacteriosis was available in Aviapp.

Evaluation of the level of dysbacteriosis in different groups (shown in Figure 3) shows that herds treated with penicillin and tylosin have a steeper slope in the level of dysbacteriosis compared to herds that did not receive any treatment and those that did not. They received amoxicillin, they showed.

The test is often based on the sudden clinical signs of dysbacteriosis (such as stool concentration / feed-to-water ratio), which more clearly explains the increase for tylosin and penicillin. The untreated groups already appeared to have higher levels of dysbacteriosis at a younger age and did not increase abruptly. The result was not treated.

Amoxicillin appears to be used in various early cases of dysbacteriosis. However, the rate of increase with penicillin and tylosin is more stable than with amoxicillin.

In addition, the overall degrees of dysbacteriosis are higher in the amoxicillin-treated groups.

All designs show a peak around 22 to 24 days old with a secondary peak appearing around 30 days old.

Secondary pyctane occurs more frequently in the amoxicillin and penicillin-treated groups than in the untreated and tylosin-treated groups.

This suggests that relapse of enteritis / dysbacteriosis occurs less frequently when dysbacteriosis is treated with tylosin.

Objective evaluation of farm information is essential to evaluate or compare the performance of a given product under farm conditions.

It complements farm trials for veterinarians. Collecting such farm information is not always easy, and Aviapp, Huvepharma’s health platform, can help collect this information.


Aviapp is a global health platform from Huvepharma that structurally improves the health, well-being and performance of broilers. It is based on direct understanding and is easy to use and allows you to gather important information about your meat herds.

Therapeutic information.

Health Control -49 examines factors for accountability.

Hall Management – Bed, Climate Rating

Technical information – water and feed consumption, mortality

Coccidiosis programs, etc., such as nutrition

Aviapp allows you to compare this information in a structured and standard way at any time and compare it with other users of the platform in a specific region, country or globally. Definite essential decisions help for best performance.